Kawasaki Disease

My sister Irenie went to the Doctor yesterday because she has to send her son to his Pediatrician due to his on and off fever. I told her that it is probably tonsillitis just like Mj’s and the other kids in the neighborhood but she deprived the idea. Well, it was good idea though for her to send Yan2x to his Doctor at least she would know the exact medicines they have to buy for him.

When they went back home, she told me that I was right, Yan2x really had tonsillitis that is why his fever got back, she already bought medicines for him. When she was there, she was able to talk a lot of mother there whose kids had ailments too and one of those that they talked about, is the Kawasaki Disease. It is a rare diseases that attack kids less than 5 years old, I researched the disease in Google and this is what I found:

Kawasaki disease (also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis and Kawasaki syndrome) is an inflammation (vasculitis) of the middle-sized arteries. It affects many organs, including the skin, mucous membranes, lymph nodes, and blood vessel walls, but the most serious effect is on the heart where it can cause severe aneurysmal dilations. Without treatment, mortality may approach 1%, usually within 6 weeks of onset. With treatment, mortality is <0.01% in the U.S.[1] There is often a pre-existing viral infection that may play some role in pathogenesis. The conjunctival and oral mucosa, along with the epidermis (skin), becomes erythmatous (red and inflammed). Edema is often seen in the hands and feet and the cervical lymph nodes are often enlarged. Also, some degree of fever is often noted. Twenty percent of children affected have cardiovascular sequelae. Causes:

Like all autoimmune diseases, the cause of Kawasaki disease is presumably the interaction of genetic and environmental factors, possibly including an infection. The specific cause is unknown,[5][6][7] but current theories center primarily on immunological causes for the disease. Evidence increasingly points to an infectious etiology,[8] but debate continues on whether the cause is a conventional antigenic substance or a superantigen.[9] Children’s Hospital Boston reports that “[s]ome studies have found associations between the occurrence of Kawasaki disease and recent exposure to carpet cleaning or residence near a body of stagnant water; however, cause and effect have not been established.”[4] An association has been identified with a SNP in the ITPKC gene, which codes an enzyme that negatively regulates T-cell activation.[10] An additional factor that suggests genetic susceptibility is the fact that regardless of where they are living, Japanese children are more likely than other children to contract the disease.[4] The HLA-B51 serotype has been found to be associated with endemic instances of the disease.

One of our neighbors had a one kid who got this disease and mind you, one dosage was worth P100, 000.00 and they have to buy that at instant or else their son would be paralyzed. Good thing that the wife has jewelries to pawn, that helps them a lot, not to mention that they have to buy a total of 3 dosages.

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One Response to “Kawasaki Disease”

  1. Yami says:

    My son underwent the same ordeal with Kawasaki in 2004. Ang hirap, we also spent more than P100k for the treatment.

    You may want to check my post abt. it. Thanks.

    http://penname30.blogspot.com/2009/04/my-sons-brush-with-kawasaki-syndrome.html